Description

7-Fluoroisobenzofuran-1(3H)-One is a versatile fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which incorporates both a lactone and a fluorine atom, making it a critical precursor for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in developing novel herbicides and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for fluorinated polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design of fluorinated probes and tags for studying biological mechanisms and diagnostics.
• Custom Synthesis: Employed in contract research and manufacturing (CRO/CMO) for bespoke chemical synthesis projects.

Basic Information

Product Name	7-Fluoroisobenzofuran-1(3H)-One
CAS No.	2211-82-7
Molecular Formula	C8H5FO2
Molecular Weight	152.12 g/mol
Synonyms	7-Fluorophthalide; 7-Fluoro-1(3H)-isobenzofuranone; 7-Fluoro-3H-isobenzofuran-1-one; 7-Fluorophthalan-1-one; 1-Oxo-7-fluoroisobenzofuran; 7-Fluoro-1-oxoisobenzofuran; 7-Fluoro-1-oxo-1,3-dihydroisobenzofuran; 7-Fluoro-3H-2-benzofuran-1-one
EINECS	Contact for details

Quality Control

Our 7-Fluoroisobenzofuran-1(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.