Description

Tdp-Glucose CAS NO 2196-62-5 is a specialized nucleotide sugar derivative, specifically thymidine diphosphate glucose, which serves as a crucial activated sugar donor in enzymatic glycosylation reactions. This high-purity biochemical is essential for research and production in carbohydrate chemistry and glycobiology, where precise and efficient glycosyl transfer is required. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical developers working on carbohydrate-based drug discovery, enzyme characterization, and the synthesis of complex oligosaccharides.

Application

• Enzymatic Glycosylation Substrate: Acts as a key donor substrate for glycosyltransferases in the synthesis of glycoconjugates, oligosaccharides, and glycolipids.
• Biochemical Research: Used in enzyme kinetics studies, inhibition assays, and mechanistic investigations of glycosyltransferase enzymes.
• Pharmaceutical Development: Employed in the research and development of novel carbohydrate-based therapeutics, including antibiotics and anticancer agents.
• Diagnostic Reagent Manufacturing: Serves as a critical component in the production of diagnostic kits and reagents for studying metabolic pathways.
• Glycoengineering: Utilized in the engineering of cell surfaces and the production of recombinant glycoproteins with defined glycosylation patterns.

Basic Information

Product Name	Tdp-Glucose
CAS No.	2196-62-5
Molecular Formula	C16H24N2O16P2
Molecular Weight	562.31 g/mol
Synonyms	Thymidine 5'-diphosphoglucose; TDP-Glucose; TDPG; Thymidine diphosphate D-glucose; dTDP-Glucose; 5'-TDP-Glucose; Thymidine 5'-(trihydrogen diphosphate) P'-α-D-glucopyranosyl ester; dTDP-α-D-glucose
EINECS	218-603-4

Quality Control

Our Tdp-Glucose is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be provided to meet the requirements of cGMP and other regulatory frameworks for advanced biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate and keep frozen. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	5.0 - 7.0
Biological Activity (Enzymatic Assay)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.