Description

Estrone Heptafluorobutyrate is a high-purity, synthetic steroid derivative, specifically a heptafluorobutyryl ester of estrone. This compound is of significant value as a key analytical reference standard and a critical intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical companies engaged in hormone analysis, method validation, and the synthesis of novel steroid-based therapeutics.

Application

• Analytical Reference Standard: Used as a primary standard in Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) for the precise quantification and identification of estrone and related steroid hormones in complex matrices.
• Pharmaceutical Intermediate: Serves as a crucial synthetic building block in the research and development of steroidal drugs and novel therapeutic agents.
• Clinical Research & Diagnostics: Employed in the development and calibration of diagnostic assays for endocrine function, hormone level monitoring, and metabolic disorder studies.
• Forensic & Doping Control Analysis: Acts as a certified reference material in forensic toxicology and anti-doping laboratories for the detection of exogenous steroids.
• Method Development & Validation: Essential for establishing and validating new analytical protocols in compliance with Good Laboratory Practice (GLP) and other regulatory guidelines.
• Biochemical Research: Used in studies investigating estrogen receptor binding, steroid metabolism pathways, and related biochemical mechanisms.

Basic Information

Product Name	Estrone Heptafluorobutyrate
CAS No.	2192-60-1
Molecular Formula	C28H31F7O3
Molecular Weight	548.54 g/mol
Synonyms	Estrone 3-Heptafluorobutyrate; Estrone 3-HFB; E1-HFB; 3-Hydroxyestra-1,3,5(10)-trien-17-one heptafluorobutyrate; Estra-1,3,5(10)-trien-17-one, 3-(heptafluorobutoxy)-, (17β)-; Heptafluorobutyric acid estrone ester; Estrone, heptafluorobutyryl derivative
EINECS	Contact for details

Quality Control

Our Estrone Heptafluorobutyrate CAS NO 2192-60-1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and analytical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled accordingly to maintain stability. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.