Description

3-Cyano-2,2,5,5-Tetramethyl-1-Pyrrolidinyloxy is a stable nitroxide radical, widely recognized as a spin label and probe in electron paramagnetic resonance (EPR) spectroscopy. This compound matters for its critical role in studying molecular dynamics, protein structure, and membrane fluidity in complex biological and chemical systems. It is essential for researchers and manufacturers in the fields of biophysics, structural biology, polymer science, and materials research who require precise spin labeling agents.

Application

• Spin Labeling in EPR Spectroscopy: Used as a covalent or non-covalent tag to probe the local environment, mobility, and distances within proteins, nucleic acids, and membranes.
• Polymer & Materials Science: Acts as a radical probe to study polymerization kinetics, polymer chain dynamics, and the microstructure of various materials.
• Oxidation & Antioxidant Studies: Serves as a stable radical for investigating redox processes, radical scavenging activity, and antioxidant mechanisms.
• Magnetic Resonance Imaging (MRI) Contrast Agents: Utilized in the development of novel paramagnetic contrast agents for enhanced imaging.
• Nitroxide-Mediated Polymerization (NMP): Functions as a controlling agent in living radical polymerization techniques to produce polymers with well-defined architectures.
• Biophysical Research: Applied in studying lipid bilayer properties, protein folding/unfolding, and site-directed spin labeling (SDSL) experiments.

Basic Information

Product Name	3-Cyano-2,2,5,5-Tetramethyl-1-Pyrrolidinyloxy
CAS No.	2154-70-3
Molecular Formula	C9H15N2O•
Molecular Weight	167.23 g/mol
Synonyms	3-Carbamoyl-2,2,5,5-tetramethylpyrrolidine-1-oxyl; 3-Cyano-PROXYL; 3-Cyano-2,2,5,5-tetramethylpyrrolidin-1-oxyl; 3-Cyano-2,2,5,5-tetramethyl-1-pyrrolidinyloxy free radical; 3-Cyano-PROXYL nitroxide radical; 3-CP; 1-Oxyl-2,2,5,5-tetramethyl-3-cyanopyrrolidine; CTMPO
EINECS	218-447-5

Quality Control

Our 3-Cyano-2,2,5,5-Tetramethyl-1-Pyrrolidinyloxy is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. We adhere to relevant industry standards to support your R&D and manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C) under an inert atmosphere to prevent oxidation. Keep away from strong reducing agents.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
EPR Analysis	Single radical species present
Melting Point	Contact for details
Residue on Ignition	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.