Description

n-Acetyl-S-(1,2-Dichlorovinyl)-L-Cysteine is a specialized, high-purity biochemical derivative of L-cysteine, identified by CAS number 2148-31-4. This compound serves as a critical reference standard and intermediate in advanced toxicological and metabolic research, particularly in the study of xenobiotic metabolism and biomarker identification. It is essential for research and development laboratories in the pharmaceutical, agrochemical, and environmental safety sectors that require precise analytical standards for method validation and metabolite characterization.

Application

• Metabolite Reference Standard: Used as a certified reference material (CRM) for the accurate quantification of specific mercapturic acid pathway metabolites in biological samples.
• Toxicology Research: Critical for studying the metabolic fate and detoxification pathways of chlorinated hydrocarbons, aiding in risk assessment and safety evaluations.
• Biomarker Development: Employed in the development and validation of analytical methods (LC-MS/MS, GC-MS) for detecting exposure biomarkers in occupational and environmental health studies.
• Pharmaceutical Impurity Profiling: Acts as a synthetic intermediate or a comparative standard in the impurity identification of drug candidates and active pharmaceutical ingredients (APIs).
• Enzymology Studies: Utilized as a substrate or inhibitor in research focused on glutathione S-transferase (GST) and other conjugating enzyme activities.

Basic Information

Product Name	n-Acetyl-S-(1,2-Dichlorovinyl)-L-Cysteine
CAS No.	2148-31-4
Molecular Formula	C7H9Cl2NO3S
Molecular Weight	270.12 g/mol
Synonyms	N-Acetyl-S-(1,2-dichlorovinyl)-L-cysteine; N-Acetyl-S-(1,2-dichloroethenyl)-L-cysteine; 1,2-Dichlorovinylmercapturic Acid; DCVMA; (2R)-2-Acetamido-3-[(1,2-dichloroethenyl)sulfanyl]propanoic Acid; Trichloroethylene Metabolite S-(1,2-Dichlorovinyl)-N-acetyl-L-cysteine; N-Acetyl-S-(Dichlorovinyl)-L-cysteine; AC-DCVC
EINECS	Contact for details

Quality Control

Our n-Acetyl-S-(1,2-Dichlorovinyl)-L-Cysteine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant industry guidelines for reference standards, ensuring data integrity for your research and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.