Description

4-(Diphenylphosphino)Benzoic Acid is a versatile organophosphorus ligand and building block, recognized for its unique combination of a phosphine donor group and a carboxylic acid functionality. This bifunctional structure makes it a critical intermediate in the synthesis of advanced catalysts and materials, enabling precise control in cross-coupling and other transition metal-catalyzed reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel compounds and catalytic systems.

Application

• Catalyst Ligand Synthesis: A key precursor for constructing sophisticated bidentate and hybrid ligands used in palladium, rhodium, and nickel-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira).
• Pharmaceutical Intermediates: Serves as a building block in the research and development of active pharmaceutical ingredients (APIs), particularly where phosphine-based metal complexes are required.
• Material Science: Used in the development of functionalized polymers, metal-organic frameworks (MOFs), and surface-modifying agents due to its ability to coordinate to metals and participate in further chemical reactions.
• Agrochemical Research: Employed in the synthesis of novel ligands for catalysts used in creating advanced pesticides and herbicides.
• Homogeneous Catalysis: Direct use or modification for creating tailored homogeneous catalysts for fine chemical and specialty chemical production.
• Chelating Agent: Acts as a chelating agent for various transition metals, useful in extraction processes and analytical chemistry.

Basic Information

Product Name	4-(Diphenylphosphino)Benzoic Acid
CAS No.	2129-31-9
Molecular Formula	C19H15O2P
Molecular Weight	306.30 g/mol
Synonyms	(4-Carboxyphenyl)diphenylphosphine; 4-(Diphenylphosphanyl)benzoic acid; Benzoic acid, 4-(diphenylphosphino)-; p-(Diphenylphosphino)benzoic acid; DPPBA; 4-Diphenylphosphinobenzoic acid; 4-(DPP)Benzoic Acid; 4-Carboxybenzeneyldiphenylphosphine
EINECS	218-342-6

Quality Control

Our 4-(Diphenylphosphino)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 15-25°C. Due to its sensitivity to oxidation, the container should be flushed with inert gas after each opening to maintain product integrity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.