Description

4-Pentyn-2-ol is a versatile terminal alkyne bearing a secondary hydroxyl group, making it a valuable bifunctional building block in synthetic organic chemistry. This compound is particularly significant for its role in click chemistry and metal-catalyzed coupling reactions, enabling the efficient construction of complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for drug discovery and specialty polymer synthesis.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of active pharmaceutical ingredients (APIs) and bioactive molecules via Huisgen cycloaddition (click chemistry).
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and plant growth regulators that incorporate alkyne functionalities.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, dendrimers, and conductive materials.
• Chemical Biology Probes: Utilized in bioconjugation strategies to label proteins, nucleic acids, and other biomolecules for imaging and diagnostic applications.
• Ligand & Catalyst Development: Acts as a precursor for chiral ligands and organometallic catalysts used in asymmetric synthesis.
• Organic Synthesis Building Block: Employed in Sonogashira, Glaser, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.

Basic Information

Item	Detail
Product Name	4-Pentyn-2-ol
CAS No.	2117-11-5
Molecular Formula	C5H8O
Molecular Weight	84.12 g/mol
Synonyms	4-Pentyn-2-ol; 2-Hydroxy-4-pentyne; 4-Pentyne-2-ol; 1-Methyl-3-butyn-1-ol; 3-Butyn-1-ol, 1-methyl-; 2-Pentyn-4-ol (incorrect but common isomer reference); Ethynylmethyl carbinol
EINECS	218-315-7

Quality Control

Our 4-Pentyn-2-ol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (IR, NMR), to verify identity and assay. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Due to its highly volatile and easily oxidized nature, the recommended long-term storage temperature is 2-8°C. Keep away from heat, sparks, open flames, and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.