Description

Didemethylchlorpromazine CAS NO 2095-17-2 is a key pharmaceutical intermediate and a metabolite of the antipsychotic drug chlorpromazine. This compound is of significant value in research and development for the synthesis of novel phenothiazine derivatives and for metabolic studies. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in neuropharmacology, drug metabolism, and the development of central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: Critical for the synthesis and research of phenothiazine-based antipsychotic drugs and their analogs.
• Metabolite Reference Standard: Used as a certified reference material in analytical laboratories for pharmacokinetic and bioequivalence studies of chlorpromazine.
• Biochemical Research: Employed in studies investigating the metabolic pathways, mechanisms of action, and side-effect profiles of tricyclic neuroleptics.
• Active Pharmaceutical Ingredient (API) Development: Serves as a building block in the development of new therapeutic agents targeting dopamine and other neurotransmitter receptors.
• Quality Control & Assurance: Essential for pharmaceutical QC labs to identify and quantify metabolites in drug substance and finished product analysis.

Basic Information

Product Name	Didemethylchlorpromazine
CAS No.	2095-17-2
Molecular Formula	C17H19ClN2S
Molecular Weight	318.86 g/mol
Synonyms	Nor2-Chlorpromazine; Desdimethylchlorpromazine; 2-Chloro-10H-phenothiazine-10-propanamine; 3-(2-Chloro-10H-phenothiazin-10-yl)-N-methylpropan-1-amine; Chlorpromazine Desdimethyl Metabolite; Chlorpromazine Nor2 Metabolite; CPZ-Nor2
EINECS	Contact for details

Quality Control

Our Didemethylchlorpromazine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and MS for identification, and residual solvent analysis, to ensure it meets high-purity standards suitable for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.