Description

Pimozide CAS NO 2062-78-4 is a potent, high-purity diphenylbutylpiperidine derivative belonging to the class of typical antipsychotics. It is valued for its specific dopamine receptor antagonism, making it a critical active pharmaceutical ingredient (API) for specialized therapeutic formulations. This compound is essential for pharmaceutical manufacturers and research institutions focused on developing and producing treatments for neurological and psychiatric conditions.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of antipsychotic medications.
• Neurological Research: Used as a reference standard and tool compound in preclinical studies investigating dopamine D2 receptor pathways.
• Formulation Development: Serves as a key component in the R&D of new drug delivery systems, such as controlled-release tablets or capsules.
• Clinical Trial Material: Supplied as a high-purity compound for use in Phase I-III clinical studies for new therapeutic applications.
• Generic Drug Manufacturing: A critical raw material for companies producing generic versions of established pimozide-based therapies.
• Analytical Standard: Employed as a certified reference material (CRM) in quality control laboratories for HPLC, LC-MS, or NMR method development and validation.

Basic Information

Product Name	Pimozide
CAS No.	2062-78-4
Molecular Formula	C28H29F2N3O
Molecular Weight	461.55 g/mol
Synonyms	Pimozide; 1-[1-[4,4-Bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one; Orap; Antalon; Opiran; R-6238; McNeil-4453; Diphenylbutylpiperidine antipsychotic
EINECS	218-180-5

Quality Control

Our Pimozide is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Every batch is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via advanced techniques like HPLC and GC. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with in-house specifications aligned with ICH guidelines. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.