Description

4-[3-(2-Chloro-10H-Phenothiazin-10-Yl)Propyl]Piperazine-1-Ethanol Dihydrochloride is a high-purity, functionalized phenothiazine derivative supplied as a dihydrochloride salt. This compound is a critical pharmaceutical intermediate valued for its precise chemical structure, which serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs). It is primarily required by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in the development and production of specialized therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of tricyclic antidepressant and antipsychotic drug candidates.
• Chemical Research & Development: Used as a versatile building block for creating novel phenothiazine-based compounds with potential biological activity.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in multi-step synthetic routes for producing complex drug molecules targeting the central nervous system.
• Biochemical Research: Serves as a tool compound in pharmacological studies to investigate receptor interactions and metabolic pathways.
• Fine Chemical Manufacturing: Supplied to contract manufacturing organizations (CMOs) for custom synthesis and scale-up projects.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	4-[3-(2-Chloro-10H-Phenothiazin-10-Yl)Propyl]Piperazine-1-Ethanol Dihydrochloride
CAS No.	2015-28-3
Molecular Formula	C21H27ClN3OS • 2HCl
Molecular Weight	483.90 g/mol (for dihydrochloride salt)
Synonyms	2-Chloro-10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazine Dihydrochloride; Perphenazine Impurity Dihydrochloride; 1-[2-[4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl]ethyl] Dihydrochloride; 4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol Dihydrochloride; NSC 683919 Dihydrochloride; Perphenazine Related Compound Dihydrochloride
EINECS	Contact for details

Quality Control

Our 4-[3-(2-Chloro-10H-Phenothiazin-10-Yl)Propyl]Piperazine-1-Ethanol Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent identity, meeting the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.