Description

2-Trifluoromethylbenzoxazole is a high-value fluorinated heterocyclic building block, identified by CAS NO 2008-04-0. This compound is prized for its unique electronic properties imparted by the trifluoromethyl group, making it a critical intermediate in advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides where the benzoxazole scaffold contributes to biological activity.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its fluorine content.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and cyclizations to construct complex molecular architectures in medicinal chemistry.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the influence of the trifluoromethyl group on heterocyclic systems.

Basic Information

Product Name	2-Trifluoromethylbenzoxazole
CAS No.	2008-04-0
Molecular Formula	C8H4F3NO
Molecular Weight	187.12 g/mol
Synonyms	2-(Trifluoromethyl)-1,3-benzoxazole; Benzoxazole, 2-(trifluoromethyl)-; 2-Trifluoromethyl-1,3-benzoxazole; 2-(Trifluoromethyl)benzoxazole; α,α,α-Trifluoro-2-benzoxazolemethane
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethylbenzoxazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.