Description

Chlorocyanoacetylene is a highly reactive and versatile bifunctional organic building block, containing both a chloro and a cyano group attached to an acetylene core. This unique structure makes it a valuable precursor for synthesizing complex heterocyclic compounds and functionalized materials. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel molecular scaffolds. Its high reactivity also makes it a key intermediate in advanced material science applications.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the construction of nitrogen-containing heterocycles, such as pyrazoles, triazoles, and pyrimidines, which are common motifs in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactivity to introduce chlorinated and cyano-functionalized side chains.
• Material Science Research: Acts as a monomer or cross-linking agent in the synthesis of specialized polymers, dendrimers, and conductive organic frameworks.
• Chemical Biology Probes: Employed in click chemistry and bioorthogonal reactions to label biomolecules or create activity-based probes for enzyme studies.
• Organic Synthesis Building Block: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Sonogashira) and nucleophilic substitution reactions to create complex, multi-functional molecules.

Basic Information

Product Name	Chlorocyanoacetylene
CAS No.	2003-31-8
Molecular Formula	C3ClN
Molecular Weight	85.48 g/mol
Synonyms	Chloro-2-propynenitrile; 3-Chloropropynenitrile; Chloropropiolonitrile; 3-Chloro-2-propynenitrile; Propiolonitrile, 3-chloro-; Chloroacetylene cyanide; 2-Propynenitrile, 3-chloro-; Chlorocyanoethyne
EINECS	Contact for details

Quality Control

Our Chlorocyanoacetylene is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and reactive nature, store in a cool (15-25°C), dry, and well-ventilated area, away from heat sources and incompatible materials. Keep container tightly sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.