Description

4-Fluoro-3-Amino-Acetophenone is a versatile fluorinated aromatic ketone building block, prized for its unique combination of functional groups that enable selective chemical transformations. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical sector, where it serves as a key intermediate for active pharmaceutical ingredients (APIs). It is essential for research and production in medicinal chemistry, agrochemical development, and advanced material science.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and stability.
• Material Science Research: Serves as a monomer or precursor in the creation of specialty polymers and liquid crystals with specific optical or electronic properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex fluorinated aromatic structures via reactions like Suzuki coupling or reductive amination.
• Dye and Pigment Intermediate: Acts as a precursor in the manufacture of specialized fluorinated dyes and colorants.

Basic Information

Product Name	4-Fluoro-3-Amino-Acetophenone
CAS No.	2002-82-6
Molecular Formula	C8H8FNO
Molecular Weight	153.15 g/mol
Synonyms	1-(4-Fluoro-3-aminophenyl)ethanone; 3-Amino-4-fluoroacetophenone; 4'-Fluoro-3'-aminoacetophenone; 3-Acetylamino-4-fluorobenzene; 4-Fluoro-m-aminoacetophenone; 1-(3-Amino-4-fluorophenyl)ethan-1-one; 2002-82-6; 4-Fluoro-3-aminophenyl methyl ketone
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Amino-Acetophenone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.