Description

2-Chloro-5'-Fluoro-2'-Hydroxy-Acetophenone is a high-purity, multi-functional aromatic ketone building block of significant importance in advanced organic synthesis. Its unique halogenated and hydroxylated structure makes it a versatile precursor for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a crucial building block for developing advanced herbicides and fungicides, leveraging its halogenated aromatic core.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed as a monomer or functionalizing agent in the research of specialty polymers and advanced organic materials.
• Chemical Research & Development: A valuable standard and starting material for method development and exploratory organic chemistry in academic and industrial labs.

Basic Information

Product Name	2-Chloro-5'-Fluoro-2'-Hydroxy-Acetophenone
CAS No.	2002-75-7
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	1-(2-Chloro-5-fluorophenyl)-2-hydroxyethanone; 2-Chloro-5-fluoro-2'-hydroxyacetophenone; 2'-Hydroxy-2-chloro-5'-fluoroacetophenone; 2-Chloro-5-fluorophenacyl alcohol; 2-Chloro-α-hydroxy-5-fluoroacetophenone; 2-Chloro-5-fluorosalicylaldehyde, reduced methyl ketone; α-Hydroxy-2-chloro-5-fluoroacetophenone
EINECS	Contact for details

Quality Control

Our 2-Chloro-5'-Fluoro-2'-Hydroxy-Acetophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, GC, NMR, and IR spectroscopy. Our quality commitment ensures the material meets the stringent requirements for use as a pharmaceutical intermediate and in other critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.