Description

(2R)-2-Acetamido-3-(2-Bromophenyl)Propanoic Acid is a chiral, non-natural amino acid derivative characterized by a brominated phenyl side chain and an acetamido-protected amine. This compound serves as a high-value building block in advanced organic synthesis, offering a unique stereocenter and functional handles for further derivatization. It is primarily required by pharmaceutical R&D and fine chemical synthesis teams for developing novel active pharmaceutical ingredients (APIs) and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for targeted small molecule drugs.
• Peptidomimetics & Bioactive Molecule Synthesis: Used to incorporate a bromophenyl moiety into peptide backbones, creating analogs with enhanced stability, binding affinity, or specific biological activity.
• Chemical Biology Probes: Serves as a precursor for synthesizing labeled or tagged compounds used in mechanism-of-action studies and target identification.
• Ligand & Catalyst Development: The bromine atom provides a site for further cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), enabling the creation of complex ligands for catalysis.
• Academic & Industrial Research: Employed in methodological studies for asymmetric synthesis and as a model compound in developing new synthetic routes.

Basic Information

Product Name	(2R)-2-Acetamido-3-(2-Bromophenyl)Propanoic Acid
CAS No.	1998701-05-5
Molecular Formula	C11H12BrNO3
Molecular Weight	286.12 g/mol
Synonyms	(R)-2-Acetamido-3-(2-bromophenyl)propanoic acid; N-Acetyl-2-bromo-D-homophenylalanine; D-N-Acetyl-2-bromohomophenylalanine; (2R)-2-Acetylamino-3-(2-bromophenyl)propionic Acid; 2-Bromo-D-homophenylalanine, N-acetyl-; (R)-N-Acetyl-2-bromohomophenylalanine; 1998701-05-5; (R)-2-Acetamido-3-(2-bromophenyl)propionic acid
EINECS	Contact for details

Quality Control

Our production of (2R)-2-Acetamido-3-(2-Bromophenyl)Propanoic Acid adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Every lot is fully characterized and tested against rigorous internal specifications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.