Description

Di-tert-Butyl(3-Methyl-2-Butenyl)Phosphine is a specialized tertiary phosphine ligand, a key building block in advanced organometallic chemistry and catalysis. Its sterically hindered structure is engineered to provide exceptional control in transition metal-catalyzed reactions, enabling the synthesis of complex molecules with high selectivity. This high-purity reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries, where it facilitates the development of novel synthetic routes and active ingredients.

Application

• Ligand in Cross-Coupling Catalysis: A critical component in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Negishi) for C-C and C-X bond formation in complex molecule synthesis.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), enabling precise stereochemical control.
• Agrochemical Product Development: Facilitates the creation of novel herbicides, fungicides, and insecticides through advanced catalytic processes.
• Fine Chemical and Specialty Material Production: Employed in the synthesis of specialty polymers, liquid crystals, and electronic materials requiring high-purity intermediates.
• Academic and Industrial R&D: A valuable tool for exploring new catalytic systems and reaction methodologies in both university and corporate research laboratories.
• Asymmetric Synthesis: Serves as a precursor or auxiliary ligand in the development of chiral catalysts for enantioselective transformations.

Basic Information

Item	Detail
Product Name	Di-tert-Butyl(3-Methyl-2-Butenyl)Phosphine
CAS No.	1980039-10-8
Molecular Formula	C13H27P
Molecular Weight	214.33 g/mol
Synonyms	Di-tert-butyl(3-methylbut-2-en-1-yl)phosphine; (3-Methyl-2-butenyl)di-tert-butylphosphine; Di-tert-butyl(3,3-dimethylallyl)phosphine; P,P-Di-tert-butyl-P-(3-methyl-2-butenyl)phosphine; DTBP; Di-t-butyl(3-methyl-2-butenyl)phosphine
EINECS	Contact for details

Quality Control

Our Di-tert-Butyl(3-Methyl-2-Butenyl)Phosphine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically exceeding 97%. Each lot is characterized by NMR (1H, 13C, 31P) and GC or HPLC analysis to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its easily oxidized nature, this product must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.