Description

2-(5-Fluoro-2-Methyl-4-Nitrophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient, selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and development pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides that incorporate fluorinated aromatic systems for enhanced efficacy and stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Diagnostics: Employed in the synthesis of probes, tags, and linkers for bioconjugation and diagnostic assay development.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and catalysis studies within university and industrial research settings.

Basic Information

Product Name	2-(5-Fluoro-2-Methyl-4-Nitrophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1979186-82-7
Molecular Formula	C₁₃H₁₇BFNO₄
Molecular Weight	281.09 g/mol
Synonyms	5-Fluoro-2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nitrobenzene; (5-Fluoro-2-methyl-4-nitrophenyl)boronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-(5-fluoro-2-methyl-4-nitrophenyl)-1,3,2-dioxaborolane; 2-Methyl-5-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nitrobenzene; Pinacol (5-fluoro-2-methyl-4-nitrophenyl)boronate; 1979186-82-7; Boronic acid, B-(5-fluoro-2-methyl-4-nitrophenyl)-, 1,1,1,1-tetramethylethylene ester
EINECS	Contact for details

Quality Control

Our 2-(5-Fluoro-2-Methyl-4-Nitrophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.