Description

5-(Cyclopentyloxy)-2-Fluorophenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, particularly for candidates requiring specific fluorinated and alkoxy-substituted aromatic scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in constructing advanced herbicide and fungicide molecules, where the fluorophenyl moiety can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the synthesis of organic electronic materials, such as polymers for OLEDs or conductive films.
• Ligand and Catalyst Development: Employed in the creation of novel palladium ligands or as a precursor for functionalized catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the synthesis of fluorinated molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-(Cyclopentyloxy)-2-Fluorophenylboronic Acid
CAS No.	1960405-25-7
Molecular Formula	C₁₁H₁₄BFO₃
Molecular Weight	224.04 g/mol
Synonyms	2-Fluoro-5-(cyclopentyloxy)benzeneboronic Acid; (2-Fluoro-5-cyclopentyloxyphenyl)boronic Acid; 5-Cyclopentyloxy-2-fluorobenzeneboronic Acid; 2-Fluoro-5-(cyclopentyloxy)phenylboronic Acid; Boronic acid, B-[2-fluoro-5-(cyclopentyloxy)phenyl]-; 1960405-25-7
EINECS	Contact for details

Quality Control

Our 5-(Cyclopentyloxy)-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.