Description

(S)-3-Amino-6-((tert-Butoxycarbonyl) Amino)Hexanoic Acid is a high-purity, non-natural amino acid derivative featuring both Boc-protected and free amino functionalities, making it a versatile chiral building block for advanced synthesis. This compound is critical for researchers and manufacturers requiring precise stereochemistry and orthogonal protecting group strategies in complex molecule assembly. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of novel peptide-based therapeutics, enzyme inhibitors, and diagnostic agents. Its defined structure ensures reproducibility and quality in sensitive research and production workflows.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for metabolic and neurological disorders.
• Peptide Synthesis: Serves as a specialized, protected amino acid residue for solid-phase and solution-phase peptide synthesis (SPPS), enabling the construction of complex peptide sequences.
• Protease Inhibitor Development: Used in the design and synthesis of selective inhibitors for various proteases, relevant in oncology and antiviral research.
• Bioconjugation & Linker Chemistry: The differentially protected amino groups allow for selective conjugation to other molecules, useful in creating antibody-drug conjugates (ADCs) or diagnostic probes.
• Chemical Biology Research: Employed as a tool compound to study enzyme mechanisms or to incorporate stable, functionalized handles into biomolecules.
• Material Science: Potential monomer for creating novel functional polymers with specific chiral or bioactive properties.

Basic Information

Product Name	(S)-3-Amino-6-((tert-Butoxycarbonyl) Amino)Hexanoic Acid
CAS No.	1956436-56-8
Molecular Formula	C11H22N2O4
Molecular Weight	246.31 g/mol
Synonyms	(S)-3-Amino-6-((Boc)amino)hexanoic acid; (3S)-3-Amino-6-[[(2-methylpropan-2-yl)oxycarbonyl]amino]hexanoic acid; Boc-Dap-OH (with Dap = 2,3-diaminopropionic acid derivative); (S)-6-((tert-Butoxycarbonyl)amino)-3-aminohexanoic acid; N6-Boc-N3-H-3,6-diaminohexanoic acid (S-isomer); (S)-3,6-Diaminohexanoic acid N6-Boc derivative; A protected diamino acid building block
EINECS	Contact for details

Quality Control

Our production of (S)-3-Amino-6-((tert-Butoxycarbonyl) Amino)Hexanoic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity, essential for research and cGMP manufacturing. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for chiral purity and assay, NMR for structural confirmation, and mass spectrometry. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.