Description

tert-Butyl (2-(5-Methyl-1H-Indazol-3-Yl)Ethyl)Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a carbamate-protected amine group on an indazole-based scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of targeted small-molecule therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel drug candidates, especially in oncology and CNS disorders.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting protein kinases and other enzymatic pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Proteolysis-Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component in the design of bifunctional degraders.
• Custom Synthesis & Contract Manufacturing: A starting material or intermediate for custom API synthesis under cGMP or research-grade conditions.
• Bioconjugation & Probe Development: The carbamate-protected amine allows for deprotection and subsequent conjugation to labels, tags, or other biomolecules.
• Academic & Institutional Research: Employed in biochemical and pharmacological studies investigating indazole-based compound libraries.

Basic Information

Product Name	tert-Butyl (2-(5-Methyl-1H-Indazol-3-Yl)Ethyl)Carbamate
CAS No.	1956370-87-8
Molecular Formula	C₁₅H₂₁N₃O₂
Molecular Weight	275.35 g/mol
Synonyms	tert-Butyl N-[2-(5-methyl-1H-indazol-3-yl)ethyl]carbamate; BOC-5-Methyl-1H-indazole-3-ethylamine; 3-[2-[(tert-Butoxycarbonyl)amino]ethyl]-5-methyl-1H-indazole; 5-Methyl-1H-indazole-3-ethylamine, N-BOC-protected; N-BOC-2-(5-Methyl-1H-indazol-3-yl)ethylamine; (2-(5-Methyl-1H-indazol-3-yl)ethyl)carbamic acid tert-butyl ester; tert-Butyl (2-(5-methyl-1H-indazol-3-yl)ethyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl (2-(5-Methyl-1H-Indazol-3-Yl)Ethyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, and custom purity grades (e.g., >98%, >99%) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.