Description

Sodium 2-(5-(Trifluoromethyl)Pyridin-2-Yl)Acetate is a high-value, organofluorine building block essential for modern synthetic chemistry. This compound is a key intermediate in the development of advanced pharmaceuticals and agrochemicals, where the trifluoromethylpyridine moiety imparts desirable metabolic stability and bioavailability. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules. Its utility as a versatile synthon makes it critical for innovation in drug discovery and crop protection.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials that require fluorinated aromatic components.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.
• Life Science Reagents: Used to create biochemical probes and labeled compounds for diagnostic and research applications.

Basic Information

Product Name	Sodium 2-(5-(Trifluoromethyl)Pyridin-2-Yl)Acetate
CAS No.	1956366-39-4
Molecular Formula	C8H5F3NNaO2
Molecular Weight	227.11 g/mol
Synonyms	Sodium (5-(Trifluoromethyl)pyridin-2-yl)acetate; 2-(5-(Trifluoromethyl)-2-pyridinyl)acetic acid sodium salt; (5-Trifluoromethyl-2-pyridyl)acetic acid sodium salt; Sodium 2-(5-Trifluoromethyl-2-pyridyl)acetate; 2-Pyridineacetic acid, 5-(trifluoromethyl)-, sodium salt (1:1); TFMPAA sodium salt; 5-CF3-2-PyAA sodium salt
EINECS	Contact for details

Quality Control

Our Sodium 2-(5-(Trifluoromethyl)Pyridin-2-Yl)Acetate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and agrochemical customers. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤3.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.