Description

3-Amino-4-Bromo-2-Chlorobenzonitrile is a high-purity, multi-functional aromatic nitrile building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogenated and aminated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in the development of kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its halogen and amino groups contribute to biological activity and selectivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex azo dyes and high-performance pigments.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the presence of bromo and amino groups.
• Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and synthetic methodology development.

Basic Information

Product Name	3-Amino-4-Bromo-2-Chlorobenzonitrile
CAS No.	1956335-13-9
Molecular Formula	C7H4BrClN2
Molecular Weight	231.48 g/mol
Synonyms	4-Bromo-2-chloro-3-aminobenzonitrile; 2-Chloro-3-amino-4-bromobenzonitrile; 3-Amino-4-bromo-2-chlorobenzene carbonitrile; Benzonitrile, 3-amino-4-bromo-2-chloro-; 1956335-13-9; 4-Bromo-2-chloro-3-cyanoaniline; 2-Chloro-4-bromo-3-aminobenzonitrile
EINECS	Contact for details

Quality Control

Our 3-Amino-4-Bromo-2-Chlorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.