Description

(3-Amino-Azetidin-1-Yl)-Cyclopropyl-Methanone, Hydrochloride (1:1) is a high-purity azetidine derivative building block of significant interest in modern pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting complex biological pathways. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries. Its well-defined structure and salt form offer advantages in solubility and handling for advanced synthetic applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in areas requiring constrained, nitrogen-containing heterocycles.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic agents.
• Process Chemistry Development: Serves as a starting material or advanced intermediate in the scale-up and optimization of API manufacturing routes.
• Bioconjugation & Probe Synthesis: Potential use in creating chemical probes or conjugates for biochemical and diagnostic applications due to its reactive amino group.
• Library Synthesis for High-Throughput Screening: Valuable scaffold for generating diverse compound libraries to identify new bioactive molecules.

Basic Information

Product Name	(3-Amino-Azetidin-1-Yl)-Cyclopropyl-Methanone, Hydrochloride (1:1)
CAS No.	1956325-48-6
Molecular Formula	C7H13ClN2O
Molecular Weight	176.65 g/mol
Synonyms	Cyclopropyl(3-aminoazetidin-1-yl)methanone hydrochloride; 1-(Cyclopropylcarbonyl)-3-aminoazetidine hydrochloride; 3-Amino-1-(cyclopropanecarbonyl)azetidine hydrochloride; (3-Aminoazetidin-1-yl)(cyclopropyl)methanone HCl; Azetidine, 3-amino-1-(cyclopropylcarbonyl)-, hydrochloride; N-(3-Aminoazetidin-1-yl)cyclopropanecarboxamide hydrochloride (tautomeric form); CPAM-HCl
EINECS	Contact for details

Quality Control

Our (3-Amino-Azetidin-1-Yl)-Cyclopropyl-Methanone, Hydrochloride (1:1) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.