Description

2-Fluoro-N,2-Dimethylpropan-1-Amine Hcl is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. Its unique fluorinated dimethylpropylamine structure makes it a valuable synthon for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to introduce fluorine atoms for modulating biological activity and physicochemical properties. The CAS number for this substance is 1956318-97-0.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides where the fluorine atom enhances bioavailability and environmental stability.
• Chemical Biology & Proteomics: Serves as a versatile amine component for creating fluorinated probes, tags, and linkers for studying biological systems.
• Material Science: Employed in the research of fluorinated polymers and specialty coatings to impart specific surface properties.
• Academic & Industrial R&D: A critical reagent for method development and exploratory synthesis in organic and medicinal chemistry laboratories.
• Ligand & Catalyst Development: Acts as a precursor for nitrogen-containing ligands used in asymmetric catalysis and transition metal complexes.

Basic Information

Item	Details
Product Name	2-Fluoro-N,2-Dimethylpropan-1-Amine Hcl
CAS No.	1956318-97-0
Molecular Formula	C6H15ClFN
Molecular Weight	155.64 g/mol
Synonyms	1-Propanamine, 2-fluoro-N,2-dimethyl-, hydrochloride; 2-Fluoro-N,2-dimethylpropan-1-amine hydrochloride; 2-Fluoro-N,N,2-trimethylpropan-1-amine hydrochloride (common misnomer); 2-Fluoro-2-methyl-N-methylpropylamine hydrochloride; N,2-Dimethyl-2-fluoropropan-1-amine HCl; Fluorodimethylpropylamine hydrochloride; (2-Fluoro-2-methylpropyl)(methyl)amine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-N,2-Dimethylpropan-1-Amine Hcl is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.