Description

Benzyl (3,3-Difluorocyclobutyl)(Methyl)Carbamate (Wxc04362) is a high-purity, advanced pharmaceutical intermediate featuring a unique difluorocyclobutyl carbamate structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to incorporate fluorinated motifs for enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those requiring fluorinated cyclobutane scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the impact of difluorocyclobutyl groups on potency and pharmacokinetic properties.
• API Process Development: Serves as a critical intermediate in the scale-up and optimization of synthetic routes for potential Active Pharmaceutical Ingredients.
• Proteolysis-Targeting Chimera (PROTAC) & Degrader Development: A valuable component for constructing linkers or warheads in targeted protein degradation therapeutics.
• Agrochemical Synthesis: Potential intermediate for developing new generation pesticides and herbicides with improved efficacy.
• Material Science Research: Exploration of its use in creating specialty polymers or coatings with unique properties derived from the fluorinated ring.

Basic Information

Product Name	Benzyl (3,3-Difluorocyclobutyl)(Methyl)Carbamate (Wxc04362)
CAS No.	1956306-91-4
Molecular Formula	C14H17F2NO2
Molecular Weight	269.29 g/mol
Synonyms	Carbamic acid, N-(3,3-difluorocyclobutyl)-N-methyl-, phenylmethyl ester; Benzyl N-(3,3-difluorocyclobutyl)-N-methylcarbamate; WXC-04362; WXC04362; (3,3-Difluorocyclobutyl)(methyl)carbamic acid benzyl ester; N-Benzyloxycarbonyl-N-methyl-3,3-difluorocyclobutanamine; N-Cbz-N-methyl-3,3-difluorocyclobutanamine
EINECS	Contact for details

Quality Control

Our Benzyl (3,3-Difluorocyclobutyl)(Methyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.