Description

Nbd-Pen CAS NO 1955505-54-0 is a specialized chemical compound, a derivative of 7-nitrobenz-2-oxa-1,3-diazole (NBD) conjugated with a penicillamine moiety. This compound is valued for its role as a versatile fluorescent probe and labeling reagent in advanced biochemical and pharmaceutical research. It is primarily needed by research scientists and process developers in the fields of bioconjugation, proteomics, and medicinal chemistry for studying protein interactions, developing diagnostic assays, and creating targeted drug delivery systems.

Application

• Fluorescent Labeling of Biomolecules: Used to tag peptides, proteins, and antibodies for visualization and tracking in cellular and biochemical assays.
• Proteomics Research: Employed in activity-based protein profiling (ABPP) to study enzyme function and identify active sites.
• Drug Discovery & Development: Serves as a key intermediate in the synthesis of fluorescently-labeled drug candidates and targeted therapeutics.
• Diagnostic Assay Development: Utilized in the creation of sensitive fluorescent-based diagnostic kits and biosensors.
• Bioconjugation Chemistry: Acts as a reactive handle for attaching fluorophores to thiol-containing molecules via its penicillamine-derived structure.
• Material Science: Applied in the surface functionalization of nanoparticles and other materials for bio-imaging applications.

Basic Information

Item	Details
Product Name	Nbd-Pen
CAS No.	1955505-54-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NBD-Penicillamine; 7-Nitrobenz-2-oxa-1,3-diazol-4-yl Penicillamine; NBD Penicillamine; NBD-D-Penicillamine; NBD-Cysteine derivative; Fluorescent Penicillamine Probe; NBD Thiol Labeling Reagent; 4-((R)-2-Amino-2-carboxy-1-methyl-ethylsulfanyl)-7-nitro-benzofurazan
EINECS	Contact for details

Quality Control

Our Nbd-Pen is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.