Description

2-(1-(4-Fluorophenyl)Cyclopropyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient, selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing fluorinated biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the fluorophenyl group for enhanced biological activity and stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as polymers for OLEDs or OFETs.
• Chemical Biology & Probe Development: Employed in the synthesis of fluorescent tags, molecular probes, and bioconjugation reagents for diagnostic and research applications.
• Academic & R&D Laboratories: A versatile reagent for methodological development in organic synthesis and catalysis studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific fluorinated, cyclopropyl-containing structures.

Basic Information

Product Name	2-(1-(4-Fluorophenyl)Cyclopropyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1953178-20-5
Molecular Formula	C₁₅H₂₀BFO₂
Molecular Weight	262.13 g/mol
Synonyms	4,4,5,5-Tetramethyl-2-[1-(4-fluorophenyl)cyclopropyl]-1,3,2-dioxaborolane; 1-(4-Fluorophenyl)cyclopropane-1-boronic acid pinacol ester; [1-(4-Fluorophenyl)cyclopropyl]boronic acid pinacol ester; (1-(4-Fluorophenyl)cyclopropyl)boronic acid pinacol ester; 2-[1-(4-Fluorophenyl)cyclopropyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Fluorophenylcyclopropylboronic acid pinacol ester; Pinacol [1-(4-fluorophenyl)cyclopropyl]boronate
EINECS	Contact for details

Quality Control

Our 2-(1-(4-Fluorophenyl)Cyclopropyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (H-NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.