Description

[3-(Difluoromethyl)-1-Methyl-Pyrazol-4-Yl]Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced fungicides, herbicides, and insecticides, leveraging the difluoromethyl pyrazole moiety for enhanced bioactivity.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology & Probe Development: Employed in the construction of molecular probes and bioconjugates for studying biological pathways and diagnostic applications.
• Catalyst & Ligand Design: Utilized as a starting material for developing novel boron-containing catalysts and ligands for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	[3-(Difluoromethyl)-1-Methyl-Pyrazol-4-Yl]Boronic Acid
CAS No.	1951411-54-3
Molecular Formula	C6H9BF2N2O2
Molecular Weight	189.96 g/mol
Synonyms	[3-(Difluoromethyl)-1-methyl-1H-pyrazol-4-yl]boronic acid; (3-(Difluoromethyl)-1-methyl-1H-pyrazol-4-yl)boronic acid; 1-Methyl-3-(difluoromethyl)-1H-pyrazol-4-ylboronic acid; 4-Borono-3-(difluoromethyl)-1-methyl-1H-pyrazole; 3-(Difluoromethyl)-1-methyl-4-pyrazoleboronic acid; Boronic acid, B-[3-(difluoromethyl)-1-methyl-1H-pyrazol-4-yl]-; DFMP-BA
EINECS	Contact for details

Quality Control

Our [3-(Difluoromethyl)-1-Methyl-Pyrazol-4-Yl]Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our production adheres to cGMP guidelines where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under inert atmosphere (argon/nitrogen) when opening to prevent degradation. For long-term storage, consider storing under an inert gas blanket in a freezer (-20°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.