Description

Ceftizoxime CAS NO 1942004-69-4 is a third-generation cephalosporin antibiotic belonging to the class of β-lactam antibiotics. It is valued for its broad-spectrum activity against a wide range of Gram-positive and Gram-negative bacteria, including many β-lactamase-producing strains. This makes it a critical active pharmaceutical ingredient (API) for the formulation of injectable antibiotics used in clinical settings. Pharmaceutical manufacturers and research institutions globally rely on high-purity Ceftizoxime for developing effective treatments for serious infections.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in the manufacture of sterile injectable antibiotic formulations.
• Research and development of new antibacterial therapies and combination drugs in pharmaceutical R&D laboratories.
• Used in clinical studies and trials to evaluate efficacy against resistant bacterial strains.
• Reference standard in quality control and analytical testing for antibiotic potency and purity.
• Potential intermediate in the synthesis of more advanced cephalosporin derivatives.

Basic Information

Product Name	Ceftizoxime
CAS No.	1942004-69-4
Molecular Formula	C13H13N5O5S2
Molecular Weight	383.41 g/mol
Synonyms	Ceftizoxime Sodium; FK 749; FR 13749; SKF 88373-Z; Ceftizox; (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Antibiotic FK 749
EINECS	Contact for details

Quality Control

Our Ceftizoxime is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting key parameters such as assay, related substances, and residual solvents. Our quality commitment aligns with cGMP principles to support our global customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
pH (1% solution)	4.5 - 6.5
Specific Optical Rotation	-55° to -65°

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.