Description

Sulfo-Cy 3 Carboxylic Acid is a water-soluble, near-infrared fluorescent dye derivative functionalized with a carboxylic acid group for bioconjugation. This compound is essential for creating stable, bright, and biocompatible fluorescent probes for advanced bioimaging and diagnostic applications. It is primarily needed by researchers and manufacturers in the life sciences, pharmaceutical development, and in vitro diagnostics sectors for labeling proteins, antibodies, and other biomolecules.

Application

• Bioconjugation and Probe Synthesis: Used as a key intermediate for covalently attaching the bright, stable Cy3 fluorophore to antibodies, proteins, peptides, and oligonucleotides via its carboxylic acid group.
• Fluorescence Microscopy & Imaging: Enables the preparation of high-performance fluorescent labels for cellular imaging, tissue staining, and super-resolution microscopy techniques.
• Flow Cytometry: Serves in the development of fluorescent antibody conjugates and other detection reagents for multiparameter cell analysis and immunophenotyping.
• In Vitro Diagnostics (IVD): Utilized in the manufacture of fluorescent detection components for immunoassays, lateral flow tests, and other clinical diagnostic platforms.
• Drug Discovery & Development: Applied in high-throughput screening (HTS), target engagement studies, and pharmacokinetic research using fluorescently tagged compounds.
• Nucleic Acid Labeling: Can be used to synthesize labeled nucleotides or probes for fluorescence in situ hybridization (FISH) and genomic analysis.

Basic Information

Product Name	Sulfo-Cy 3 Carboxylic Acid
CAS No.	1941997-61-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Sulfo-Cyanine3 Carboxylic Acid; Sulfo Cy3-COOH; Cy3 Sulfonated Carboxylic Acid; Sulfo-Cy3 Acid; Water-soluble Cy3 Carboxylic Acid; 2-((1E,3E)-5-((E)-1-(5-Carboxypentyl)-3,3-dimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indol-1-ium-5-sulfonate; Sulfoindocyanine green carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our Sulfo-Cy 3 Carboxylic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive life science applications. A comprehensive Certificate of Analysis (COA) detailing purity, absorbance/fluorescence properties, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Dark green to purple solid
Identification (HPLC/UV-Vis)	Conforms
Purity (HPLC)	≥95%
Absorption Maximum (λmax)	~554 nm
Emission Maximum (λem)	~570 nm
Extinction Coefficient (ε)	Contact for details
Water Content (KF)	<5%
Solubility	Soluble in water, DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.