Description

(R)-n-Benzyl-2-(3-(3,5-Bis(Trifluoromethyl)Phenyl)Thioureido)-N,3,3-Trimethylbutanamide is a high-purity, chiral thiourea derivative of significant interest in advanced organic synthesis. Its value lies in its role as a sophisticated building block and potential ligand or intermediate for pharmaceutical research and specialty chemical development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries, where its unique trifluoromethylated aromatic and thiourea functionalities enable the creation of novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological or metabolic diseases.
• Catalyst/Ligand Precursor: Used in the development of asymmetric catalysts or as a ligand for metal complexes in stereoselective synthesis.
• Agrochemical Research: Acts as a building block for novel herbicides, fungicides, or insecticides, leveraging the bioactivity often associated with the thiourea and trifluoromethyl groups.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique thermal or surface properties.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme inhibition or protein-ligand interactions due to its potential hydrogen-bonding capabilities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	(R)-n-Benzyl-2-(3-(3,5-Bis(Trifluoromethyl)Phenyl)Thioureido)-N,3,3-Trimethylbutanamide
CAS No.	1938090-71-1
Molecular Formula	C24H27F6N3OS
Molecular Weight	511.55 g/mol
Synonyms	(R)-N-Benzyl-2-[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino-N,3,3-trimethylbutanamide; (R)-1-Benzyl-2-((3,5-bis(trifluoromethyl)phenyl)carbamothioylamino)-N,3,3-trimethylbutanamide; (R)-2-(3-(3,5-Bis(trifluoromethyl)phenyl)thioureido)-N-benzyl-N,3,3-trimethylbutanamide; CAS 1938090-71-1; (R)-enantiomer of the thiourea derivative; BTTB Amide (R)-isomer
EINECS	Contact for details

Quality Control

Our (R)-n-Benzyl-2-(3-(3,5-Bis(Trifluoromethyl)Phenyl)Thioureido)-N,3,3-Trimethylbutanamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including chiral purity verification, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity (typically ≥95% by HPLC), and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.