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2-Fluoro-6-Formylphenylboronic Acid CAS NO 1938062-31-7


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CAS No.:1938062-31-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Fluoro-6-Formylphenylboronic Acid is a high-value, multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a formyl and a boronic acid group on a fluorinated aromatic ring, makes it an indispensable reagent for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in Suzuki-Miyaura cross-coupling and other transition-metal catalyzed reactions.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting various therapeutic areas.
  • Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorine atom and boronic acid handle enable precise structural modifications.
  • Material Science Research: Employed in the creation of advanced organic materials, such as organic light-emitting diodes (OLEDs) and liquid crystals, where its functional groups allow for precise polymerization or functionalization.
  • Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the synthesis of molecular probes used in diagnostic assays and imaging.
  • Cross-Coupling Reactions: Primarily utilized in Suzuki-Miyaura cross-coupling to form biaryl and other C-C bonds, a cornerstone reaction in medicinal and process chemistry.
  • Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name 2-Fluoro-6-Formylphenylboronic Acid
CAS No. 1938062-31-7
Molecular Formula C7H6BFO3
Molecular Weight 167.93 g/mol
Synonyms (2-Fluoro-6-formylphenyl)boronic acid; 2-Fluoro-6-carboxybenzene boronic acid; 2-Fluoro-6-formylbenzeneboronic acid; 2-Formyl-3-fluorophenylboronic acid; 3-Fluoro-2-formylphenylboronic acid; Boronic acid, B-(2-fluoro-6-formylphenyl)-; 2-Fluoro-6-formylphenyl-B(OH)2
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Quality Control

Our 2-Fluoro-6-Formylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request. We support compliance with relevant regulatory frameworks for research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder or crystalline solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Heavy Metals < 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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