Description

2-Propanesulfinamide, n-[(1S)-1-[1,1'-Biphenyl]-2-Yl-2-(Diphenylphosphino)Ethyl]-2-Methyl-, [S(R)]- is a high-value, chiral sulfinamide-phosphine hybrid ligand, a key building block in asymmetric synthesis. Its unique bifunctional structure, combining a sulfinamide and a diphenylphosphino group, enables exceptional stereocontrol in transition metal-catalyzed reactions. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries developing novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• As a chiral ligand in asymmetric hydrogenation, hydroformylation, and cross-coupling reactions.
• For the synthesis of pharmaceutical intermediates requiring high enantiomeric purity.
• In the development of catalytic systems for the production of specialty and fine chemicals.
• As a key reagent in academic and industrial research exploring new asymmetric methodologies.
• For the preparation of chiral auxiliaries and catalysts used in organic synthesis.

Basic Information

Product Name	2-Propanesulfinamide, n-[(1S)-1-[1,1'-Biphenyl]-2-Yl-2-(Diphenylphosphino)Ethyl]-2-Methyl-, [S(R)]-
CAS No.	1936438-14-0
Molecular Formula	C36H34NOPS
Molecular Weight	559.70 g/mol
Synonyms	(SR)-N-[(1S)-1-([1,1'-Biphenyl]-2-yl)-2-(diphenylphosphanyl)ethyl]-2-methylpropane-2-sulfinamide; (SR)-N-[(1S)-1-([1,1'-Biphenyl]-2-yl)-2-(diphenylphosphino)ethyl]-2-methylpropane-2-sulfinamide; (SR)-N-[(1S)-1-(Biphenyl-2-yl)-2-(diphenylphosphanyl)ethyl]-2-methylpropane-2-sulfinamide; Chiral Sulfinamide-Phosphine Ligand; Bifunctional P,N-Ligand; Asymmetric Synthesis Ligand; CAS 1936438-14-0
EINECS	Contact for details

Quality Control

Our 2-Propanesulfinamide ligand is manufactured under strict quality protocols to ensure batch-to-batch consistency and high chemical purity, critical for reproducible catalytic performance. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, enantiomeric excess, and key spectroscopic data. Our quality systems support development from research to commercial scale, adhering to cGMP principles where required.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air or ambient conditions should be avoided.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.