Description

3,4,5-Trifluoro-1-(Trichloromethyl)Benzene CAS NO 1936179-69-9 is a high-value, multi-functional fluorinated aromatic building block characterized by its unique combination of fluorine and chlorine substituents. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals where its specific substitution pattern imparts critical electronic and steric properties. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated drug candidates, including kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the production of next-generation herbicides and pesticides, where the trifluoromethyl and trichloromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic materials, improving charge transport and thermal stability.
• Polymer Modification: Incorporated as a monomer or cross-linking agent to create specialty polymers with enhanced chemical resistance and unique surface properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution reactions to introduce complex fluorinated aryl groups.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	3,4,5-Trifluoro-1-(Trichloromethyl)Benzene
CAS No.	1936179-69-9
Molecular Formula	C7H2Cl3F3
Molecular Weight	247.44 g/mol
Synonyms	1-(Trichloromethyl)-3,4,5-trifluorobenzene; Benzene, 1-(trichloromethyl)-3,4,5-trifluoro-; α,α,α-Trichloro-3,4,5-trifluorotoluene; 3,4,5-Trifluorobenzotrichloride; (3,4,5-Trifluorophenyl)trichloromethane
EINECS	Contact for details

Quality Control

Our 3,4,5-Trifluoro-1-(Trichloromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed due to potential moisture sensitivity and to prevent volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.