Description

5-Bromo-1-Chloro-2-Ethoxy-3-Fluorobenzene is a high-purity, multi-substituted benzene derivative designed for advanced synthetic chemistry. This compound serves as a critical building block and intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for researchers and manufacturers requiring a reliable source of this specialized fluorinated intermediate for constructing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides, where the halogen and fluorine substitutions are crucial for biological activity.
• Material Science Research: Used in the creation of novel organic electronic materials, liquid crystals, and polymers where specific halogen/fluorine patterns dictate material properties.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and as a probe molecule in drug discovery programs.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	5-Bromo-1-Chloro-2-Ethoxy-3-Fluorobenzene
CAS No.	1936177-81-9
Molecular Formula	C8H7BrClFO
Molecular Weight	253.50 g/mol
Synonyms	1-Bromo-4-Chloro-5-Ethoxy-2-Fluorobenzene; 2-Ethoxy-3-Fluoro-5-Bromochlorobenzene; 3-Fluoro-5-Bromo-1-Chloro-2-Ethoxybenzene; 5-Bromo-1-Chloro-2-Ethoxy-3-Fluoro-Benzene; Benzene, 5-bromo-1-chloro-2-ethoxy-3-fluoro-; 1936177-81-9
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-Chloro-2-Ethoxy-3-Fluorobenzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.