Description

Glycine, n-(2,2-Dimethylpropyl)-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- is a specialized, high-purity Fmoc-protected amino acid derivative designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise molecular control and high coupling efficiency in solid-phase peptide synthesis (SPPS). It is primarily utilized by the pharmaceutical, biotechnology, and life sciences industries for the development of novel therapeutic peptides, research reagents, and complex biomolecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key building block for the controlled, stepwise assembly of custom peptide sequences.
• Pharmaceutical Research & Development: For the synthesis of peptide-based drug candidates, including hormone analogs and enzyme inhibitors.
• Bioconjugation: Used to introduce specific functional groups or linkers onto peptides for labeling or creating peptide-drug conjugates.
• Combinatorial Chemistry Libraries: Serves as a valuable reagent for generating diverse peptide libraries for high-throughput screening.
• Proteomics and Biochemical Research: Employed in the study of protein-protein interactions and the synthesis of substrate analogs.
• Custom Peptide Service Providers: A fundamental raw material for CROs and CDMOs offering bespoke peptide manufacturing.

Basic Information

Product Name	Glycine, n-(2,2-Dimethylpropyl)-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-
CAS No.	1935967-49-9
Molecular Formula	C24H29NO4
Molecular Weight	395.49 g/mol
Synonyms	Fmoc-N-(Neopentyl)glycine; N-(2,2-Dimethylpropyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycine; N-Fmoc-N-neopentylglycine; Fmoc-Npg-OH; N-Fmoc-N-neopentyl-glycine; Nα-Fmoc-Nα-(neopentyl)glycine; (2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(neopentyl)amino)acetic acid)
EINECS	Contact for details

Quality Control

Our Glycine, n-(2,2-Dimethylpropyl)-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive research and cGMP applications. All batches are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent in-process controls and final release testing protocols to meet the exacting standards of the pharmaceutical and biotechnology sectors.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.