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(9H-Fluoren-9-Yl)Methyl 4-((tert-Butoxycarbonyl)Amino)Piperidine-1-Carboxylate CAS NO 1935586-88-1
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CAS No.:1935586-88-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(9H-Fluoren-9-Yl)Methyl 4-((tert-Butoxycarbonyl)Amino)Piperidine-1-Carboxylate is a sophisticated Boc-protected piperidine derivative, serving as a critical building block in modern organic synthesis. Its primary value lies in enabling the controlled introduction of a protected amino-piperidine moiety, a structural motif of high importance in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing novel active pharmaceutical ingredients (APIs) and complex small-molecule libraries.
Application
- Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
- Peptidomimetic Chemistry: Used to incorporate constrained, nitrogen-containing heterocycles into peptide backbones to enhance metabolic stability and bioavailability.
- Protecting Group Strategy: The Fmoc and Boc protecting groups allow for orthogonal deprotection sequences, which is fundamental in solid-phase peptide synthesis (SPPS) and complex molecular assembly.
- Chemical Biology Probe Development: Serves as a scaffold for creating tool compounds and probes to study biological pathways and protein function.
- Library Synthesis for Drug Discovery: Employed in high-throughput and combinatorial chemistry to generate diverse arrays of compounds for screening against biological targets.
- Process Chemistry & Scale-Up: Provides a reliable and well-defined intermediate for the optimization and commercial-scale production of therapeutic agents.
Basic Information
| Item | Details |
|---|---|
| Product Name | (9H-Fluoren-9-Yl)Methyl 4-((tert-Butoxycarbonyl)Amino)Piperidine-1-Carboxylate |
| CAS No. | 1935586-88-1 |
| Molecular Formula | C26H32N2O4 |
| Molecular Weight | 436.55 g/mol |
| Synonyms | 1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-[(tert-butoxycarbonyl)amino]piperidine; 4-[(tert-Butoxycarbonyl)amino]-1-[(9H-fluoren-9-ylmethoxy)carbonyl]piperidine; Fmoc-4-(Boc-amino)piperidine; 1-Fmoc-4-N-Boc-piperidine; 4-(Boc-amino)-1-(Fmoc)piperidine; N-Boc-4-amino-1-Fmoc-piperidine; 1-N-Fmoc-4-N-Boc-4-aminopiperidine; Piperidine-1,4-dicarboxylic acid, 4-[(1,1-dimethylethoxy)carbonyl]amino]-, 1-(9H-fluoren-9-ylmethyl) ester |
| EINECS | Contact for details |
Quality Control
Our (9H-Fluoren-9-Yl)Methyl 4-((tert-Butoxycarbonyl)Amino)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity suitable for sensitive research and GMP-guided synthesis. Certificates of Analysis (COA) with full characterization data are provided to guarantee traceability and compliance with your project specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and should be handled with care in strong acid/organic solvent environments. For long-term storage, consider inert atmosphere conditions to maximize stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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