Description

3-Bromo-5-Fluoro-2-Iodoanisole is a high-purity, multi-halogenated anisole derivative, a key building block in advanced organic synthesis. Its precise halogen substitution pattern makes it an indispensable intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of new drug candidates, especially in kinase inhibitor and CNS-active molecule libraries.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides requiring specific halogenated aromatic cores.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as OLEDs and semiconductors, where halogen atoms tune electronic properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions due to the presence of bromo and iodo leaving groups.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Used to create tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	3-Bromo-5-Fluoro-2-Iodoanisole
CAS No.	1935372-87-4
Molecular Formula	C7H5BrFIO
Molecular Weight	330.92 g/mol
Synonyms	1-Bromo-3-fluoro-5-iodo-2-methoxybenzene; 2-Methoxy-3-bromo-5-fluoro-1-iodobenzene; 3-Bromo-5-fluoro-2-iodo-1-methoxybenzene; Benzene, 1-bromo-3-fluoro-5-iodo-2-methoxy-; 3-Br-5-F-2-I-anisole; 2-Iodo-3-bromo-5-fluoroanisole; Anisole, 3-bromo-5-fluoro-2-iodo-
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Fluoro-2-Iodoanisole is manufactured under strict quality management systems and undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Our standard quality commitment includes HPLC purity ≥97% (with higher grades available), full spectroscopic confirmation (NMR, MS, IR), and stringent control of residual solvents and heavy metals. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.