Description

(1S,3R,4S)-3-(Trifluoromethyl)-2-Oxa-5-Azabicyclo[2.2.1]Heptane(Wx120627) is a high-purity, advanced pharmaceutical intermediate featuring a unique bridged bicyclic scaffold with a strategically positioned trifluoromethyl group. This compound is valued for its role as a key chiral building block in modern medicinal chemistry, enabling the synthesis of complex molecules with enhanced metabolic stability and bioavailability. It is primarily sought after by R&D and process chemistry teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Ligand & Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probe Synthesis: Employed to build molecular tools for studying enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique properties.

Basic Information

Product Name	(1S,3R,4S)-3-(Trifluoromethyl)-2-Oxa-5-Azabicyclo[2.2.1]Heptane (Wx120627)
CAS No.	1932097-94-3
Molecular Formula	C7H8F3NO
Molecular Weight	179.14 g/mol
Synonyms	(1S,3R,4S)-3-(Trifluoromethyl)-2-oxa-5-azabicyclo[2.2.1]heptane; 2-Oxa-5-azabicyclo[2.2.1]heptane, 3-(trifluoromethyl)-, (1S,3R,4S)-; WX-120627; (1S,3R,4S)-3-Trifluoromethyl-2-oxa-5-azabicyclo[2.2.1]heptane; Bicyclic Trifluoromethyl Oxazolidine; (1S,3R,4S)-3-(Trifluoromethyl)-2-oxa-5-azabicyclo[2.2.1]heptane; Chiral Trifluoromethyl Bicyclic Intermediate
EINECS	Contact for details

Quality Control

Our (1S,3R,4S)-3-(Trifluoromethyl)-2-Oxa-5-Azabicyclo[2.2.1]Heptane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.