Description

[S(R)]-n-[(1S)-1-[2-(Diadamantanphosphino)Phenyl]Ethyl]-2-Methyl-2-Propanesulfinamide CAS NO 1929530-56-2 is a sophisticated, chiral sulfinamide ligand featuring a bulky diadamantylphosphino group, designed for high-performance asymmetric catalysis. This compound is critical for enabling highly enantioselective transformations, particularly in the synthesis of complex pharmaceutical intermediates and fine chemicals. It is an essential tool for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Asymmetric Hydrogenation: A key ligand for the enantioselective reduction of prochiral olefins, ketones, and imines in API synthesis.
• Cross-Coupling Catalysis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) where steric bulk and electronic tuning are required.
• Pharmaceutical Intermediate Synthesis: Critical for constructing chiral centers in the development of novel active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable reagent for methodology development in organic synthesis and catalysis research.
• Fine Chemical Production: Facilitates the manufacture of high-value, optically pure flavors, fragrances, and electronic chemicals.

Basic Information

Product Name	[S(R)]-n-[(1S)-1-[2-(Diadamantanphosphino)Phenyl]Ethyl]-2-Methyl-2-Propanesulfinamide
CAS No.	1929530-56-2
Molecular Formula	C31H44NOPS
Molecular Weight	509.71 g/mol
Synonyms	(S)-N-[(1S)-1-[2-(Diadamantan-1-ylphosphanyl)phenyl]ethyl]-2-methylpropane-2-sulfinamide; (S)-N-((S)-1-(2-(Diadamantan-1-ylphosphino)phenyl)ethyl)-2-methylpropane-2-sulfinamide; (S)-N-[(S)-1-[2-(Diadamantan-1-ylphosphino)phenyl]ethyl]-2-methylpropane-2-sulfinamide; (S)-N-((S)-1-(2-(Diadamantan-1-ylphosphanyl)phenyl)ethyl)-2-methylpropane-2-sulfinamide; Diadamantanphosphino Sulfinamide Ligand; Chiral Sulfinamide-Phosphine Hybrid Ligand; t-Butylsulfinamide-Diadamantylphosphine Ligand
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of [S(R)]-n-[(1S)-1-[2-(Diadamantanphosphino)Phenyl]Ethyl]-2-Methyl-2-Propanesulfinamide is characterized by advanced analytical techniques to guarantee identity, purity, and chiral integrity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to ensure long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.