Description

Human Rantes CAS NO 1927910-48-2 is a high-purity, synthetic chemokine protein, also known as CCL5, which plays a critical role in immune cell signaling and trafficking. This product is essential for researchers and developers in the life sciences sector, providing a reliable and consistent reagent for studying inflammatory pathways and immune responses. It is primarily utilized by biotechnology firms, pharmaceutical R&D departments, and academic research institutions focused on immunology, oncology, and infectious disease models.

Application

• Immunology Research: Used as a key reagent in in vitro and in vivo studies to investigate T-cell and eosinophil chemotaxis, activation, and inflammatory processes.
• Drug Discovery & Development: Serves as a target or tool compound in high-throughput screening assays for developing novel anti-inflammatory or immunomodulatory therapeutics.
• Cell Culture & Assay Development: Employed to establish robust bioassays, including migration, proliferation, and receptor binding assays, for functional characterization.
• Biomarker Studies: Utilized as a standard or calibrator in ELISA and other immunoassay platforms to quantify RANTES/CCL5 levels in clinical or preclinical samples.
• Vaccine Research: Applied in studies exploring adjuvant effects and the modulation of adaptive immune responses.
• Academic & Contract Research: A fundamental tool for basic research in university laboratories and CROs (Contract Research Organizations) studying chemokine biology.

Basic Information

Product Name	Human Rantes
CAS No.	1927910-48-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CCL5; RANTES(1-68); Chemokine (C-C motif) ligand 5; SIS-delta; T-cell-specific protein p228; Small-inducible cytokine A5; SCYA5; TCP228
EINECS	Contact for details

Quality Control

Our Human Rantes is manufactured under stringent conditions to ensure high biological activity and batch-to-batch consistency. Every lot undergoes comprehensive analytical testing, including purity assessment by HPLC and confirmation of identity. Certificates of Analysis (COA) detailing purity, endotoxin levels, and biological activity are provided to guarantee the material meets the exacting standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Biological Activity	Determined by cell migration assay
Endotoxin Level	< 1.0 EU/μg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.