Description

(Trp11,D-Phe15,16)-Cxcl12 (7-16) (Dimer) (Human, Cat, Mouse) is a synthetic, sequence-modified dimeric peptide derived from the chemokine CXCL12 (SDF-1α). This engineered compound is designed for enhanced stability and specific receptor interaction, making it a critical tool for advanced biochemical and pharmacological research. It is primarily utilized by research scientists and pharmaceutical developers in the fields of immunology, oncology, and stem cell biology to study CXCR4/CXCR7 signaling pathways, metastasis, and inflammatory processes.

Application

• Biochemical Research: Used as a potent and stable ligand for studying the structure, function, and signaling mechanisms of the CXCR4 and CXCR7 receptors.
• Oncology Studies: Employed in in vitro and in vivo models to investigate tumor metastasis, angiogenesis, and the tumor microenvironment due to the key role of the CXCL12/CXCR4 axis.
• Immunology & Inflammation Research: Applied to explore leukocyte trafficking, inflammatory responses, and autoimmune disease mechanisms.
• Stem Cell & Regenerative Medicine: Utilized in studies focusing on hematopoietic stem cell mobilization, homing, and niche interactions.
• Drug Discovery & Development: Serves as a reference standard, a tool for assay validation, or a lead compound in the development of CXCR4-targeted therapeutics.
• Academic & Pharmaceutical R&D: A key reagent for basic scientific discovery and pre-clinical development phases in both academic and industrial settings.

Basic Information

Product Name	(Trp11,D-Phe15,16)-Cxcl12 (7-16) (Dimer) (Human, Cat, Mouse)
CAS No.	1926163-84-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(Trp11,D-Phe15,16)-SDF-1α (7-16) Dimer; Dimeric CXCL12 (7-16) analog; Modified Stromal Cell-Derived Factor-1 (7-16) Dimer; [Trp11, D-Phe15, D-Phe16]-CXCL12(7-16) Dimer; SDF-1α (7-16) (Trp11, D-Phe15,16) Dimer Peptide; CXCL12-derived dimeric peptide inhibitor; CXCR4 antagonist peptide dimer
EINECS	Contact for details

Quality Control

Our peptide products are manufactured and analyzed under strict quality management systems. Each batch of (Trp11,D-Phe15,16)-Cxcl12 (7-16) (Dimer) undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure full traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	Within ± 10% of theoretical
Solubility	Soluble in water or DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.