Description

n-Boc-5-Phenyl-L-Tryptophan is a protected amino acid derivative of significant importance in advanced organic synthesis. This compound serves as a crucial building block for the construction of complex peptides and peptidomimetics, offering a versatile handle for selective deprotection and further functionalization. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for developing novel therapeutic agents targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for peptide-based drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate modified tryptophan residues with enhanced stability or altered biological activity.
• Chemical Biology Probes: Employed in the synthesis of labeled peptides or activity-based probes for studying enzyme function and protein-protein interactions.
• Medicinal Chemistry: Facilitates structure-activity relationship (SAR) studies by allowing systematic modification of peptide backbones.
• Academic & Industrial R&D: Serves as a valuable reagent for synthetic chemists in universities and contract research organizations (CROs) exploring novel synthetic methodologies.

Basic Information

Product Name	n-Boc-5-Phenyl-L-Tryptophan
CAS No.	1910135-36-2
Molecular Formula	C24H28N2O4
Molecular Weight	408.49 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)amino)-3-(5-phenyl-1H-indol-3-yl)propanoic acid; Boc-5-Phenyl-L-Trp-OH; tert-Butyl (S)-(1-((5-phenyl-1H-indol-3-yl)methyl)-2-carboxyethyl)carbamate; 5-Phenyl-L-tryptophan, N-Boc-protected; N-(tert-Butoxycarbonyl)-5-phenyl-L-tryptophan; Boc-5-Ph-L-Trp; N-Boc-5-phenyltryptophan
EINECS	Contact for details

Quality Control

Our n-Boc-5-Phenyl-L-Tryptophan is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.