Description

(3R,4S)-3-Fluorooxan-4-Ol CAS NO 1893404-91-5 is a chiral fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in providing a stereodefined scaffold that incorporates both fluorine and a hydroxyl group, enabling precise modulation of molecular properties. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the design of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Investigated as a monomer or modifier for creating specialty polymers with unique solubility or surface properties.
• Fluorine Chemistry Studies: An important reference compound in academic and industrial research exploring the effects of fluorination on conformational and electronic structure.

Basic Information

Product Name	(3R,4S)-3-Fluorooxan-4-Ol
CAS No.	1893404-91-5
Molecular Formula	C5H9FO2
Molecular Weight	120.12 g/mol
Synonyms	(3R,4S)-3-Fluorotetrahydro-2H-pyran-4-ol; (3R,4S)-3-Fluoro-4-hydroxytetrahydropyran; 3-Fluorooxan-4-ol (3R,4S)-; Tetrahydro-2H-pyran-4-ol, 3-fluoro-, (3R,4S)-; (3R,4S)-3-Fluoro-4-hydroxy-tetrahydropyran; (3R,4S)-3-Fluoro-4-hydroxypyran; (3R,4S)-3-Fluoro-4-hydroxy-3,4-dihydro-2H-pyran
EINECS	Contact for details

Quality Control

Our (3R,4S)-3-Fluorooxan-4-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric excess (ee) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with full characterization data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under a dry inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient humidity. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.