Description

3-Bromo-2,4-Dimethoxybenzonitrile is a high-purity, multi-functional chemical intermediate featuring a bromine substituent and nitrile group on a dimethoxybenzene scaffold. This compound matters for its versatility in facilitating complex molecular transformations, particularly in the synthesis of advanced pharmaceutical and agrochemical agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex heterocycles and functionalized aromatic systems.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic structure.
• Material Science Precursor: Serves as a monomer or functionalization agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig amination for carbon-carbon and carbon-heteroatom bond formation.
• Nitrile Transformation Chemistry: The cyano group can be hydrolyzed to carboxylic acids, reduced to amines, or used to form tetrazoles, expanding its utility in medicinal chemistry.
• Organic Synthesis Research: A valuable reagent in academic and industrial research labs for methodological studies and the construction of complex molecular architectures.

Basic Information

Product Name	3-Bromo-2,4-Dimethoxybenzonitrile
CAS No.	1891994-61-8
Molecular Formula	C9H8BrNO2
Molecular Weight	242.07 g/mol
Synonyms	2,4-Dimethoxy-3-bromobenzonitrile; 3-Bromo-2,4-dimethoxybenzenecarbonitrile; Benzonitrile, 3-bromo-2,4-dimethoxy-; 3-Bromo-2,4-dimethoxy-benzonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-2,4-Dimethoxybenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports applications requiring high-purity intermediates for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.