Description

4-Chloro-5-Fluoro-2-Methylphenylboronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters as a key Suzuki-Miyaura cross-coupling reagent, enabling the efficient and selective formation of carbon-carbon bonds in complex molecule assembly. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for constructing biaryl and heterobiaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Research & Development: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring specific halogenated phenyl motifs.
• Material Science & OLED Development: Serves as a building block for creating advanced organic electronic materials, including charge-transport layers and emissive materials.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands for transition metal catalysis and other organometallic complexes.
• Custom Chemical & Contract Manufacturing: A valuable starting material for custom synthesis and scale-up projects requiring precise functionalization.
• Academic & Institutional Research: Used in methodological studies and the discovery of new catalytic cross-coupling reactions.

Basic Information

Item	Details
Product Name	4-Chloro-5-Fluoro-2-Methylphenylboronic Acid Pinacol Ester
CAS No.	1885096-92-3
Molecular Formula	C13H17BClFO2
Molecular Weight	269.54 g/mol
Synonyms	4-Chloro-5-fluoro-2-methylbenzeneboronic acid pinacol ester; (4-Chloro-5-fluoro-2-methylphenyl)boronic acid pinacol ester; 2-Methyl-4-chloro-5-fluorophenylboronic acid pinacol ester; Pinacol (4-chloro-5-fluoro-2-methylphenyl)boronate; B-(4-Chloro-5-fluoro-2-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 1885096-92-3; Boronic ester derivative of 4-chloro-5-fluoro-o-xylene
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Fluoro-2-Methylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.