Description

Met-Rantes (Human) CAS NO 1883816-50-9 is a high-purity, synthetic chemokine analog designed for advanced life science research and development. This compound is critical for studying inflammatory pathways, immune cell migration, and receptor-ligand interactions in human biological systems. It is an essential reagent for pharmaceutical R&D teams, academic researchers, and diagnostic developers focused on immunology, oncology, and autoimmune disease research.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of chemokine receptor CCR5 and CCR1 signaling pathways.
• Drug Discovery & Development: Serves as a key tool compound for screening and validating potential anti-inflammatory and immunomodulatory therapeutics.
• Cell Culture & Assay Development: Employed to induce and study chemotaxis (directed cell migration) of leukocytes such as monocytes, T-cells, and eosinophils in vitro.
• Diagnostic Reagent Manufacturing: Incorporated into ELISA kits and other immunoassays for the detection and quantification of related immune markers.
• Academic & Institutional Research: Fundamental for investigating the role of RANTES/CCL5 analogs in various disease models, including HIV, atherosclerosis, and rheumatoid arthritis.
• Biotech Process Development: Used in the development and optimization of fermentation and purification processes for related protein-based products.

Basic Information

Product Name	Met-Rantes (Human)
CAS No.	1883816-50-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Methionylated RANTES (Human); Recombinant Human Met-RANTES; CCL5 Analog; [Met]RANTES; Chemokine (C-C motif) ligand 5 variant; Regulated upon Activation, Normal T-cell Expressed and Secreted variant; Met-CCL5
EINECS	Contact for details

Quality Control

Our Met-Rantes (Human) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and endotoxin testing. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing purity, biological activity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Conforms
Purity (HPLC)	≥ 95.0%
Biological Activity	Determined by chemotaxis assay
Endotoxin Level	< 1.0 EU/μg
Moisture Content (KF)	< 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.