Description

2,2,2-Trifluoro-n-(6-Fluoro-2-Nitro-Pyridin-3-Yl)-Acetamide is a high-value fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its molecular structure, featuring both trifluoroacetamide and nitro-fluoro-pyridine moieties, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Material Science: Serves as a building block for advanced materials, including liquid crystals, organic semiconductors, and specialty polymers requiring specific electronic or photophysical properties.
• Chemical Synthesis: Employed in medicinal and combinatorial chemistry for structure-activity relationship (SAR) studies and library synthesis due to its reactive nitro and amide functional groups.
• Fluorine Chemistry: A valuable reagent for introducing trifluoroacetamide protecting groups or for further functionalization reactions in complex fluoroorganic synthesis.

Basic Information

Product Name	2,2,2-Trifluoro-n-(6-Fluoro-2-Nitro-Pyridin-3-Yl)-Acetamide
CAS No.	1883537-49-2
Molecular Formula	C7H3F4N3O3
Molecular Weight	253.11 g/mol
Synonyms	N-(6-Fluoro-2-nitropyridin-3-yl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(6-fluoro-2-nitropyridin-3-yl)acetamide; 3-Acetamido-6-fluoro-2-nitropyridine, 2,2,2-trifluoro-; 1883537-49-2; 2,2,2-Trifluoroacetamide, N-(6-fluoro-2-nitro-3-pyridinyl)-; TFA-6F-2NP; 3'-Trifluoroacetamido-6'-fluoro-2'-nitropyridine
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-n-(6-Fluoro-2-Nitro-Pyridin-3-Yl)-Acetamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, for comprehensive identity and purity verification. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.