Description

6-Bromo-3-Fluoro-Pyridine-2-Carboxylic Acid Amide is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique halogenated pyridine core, which facilitates selective cross-coupling reactions and serves as a key precursor in the development of complex molecules. It is primarily sought after by research chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science: Incorporated into the design of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient pyridine ring.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	6-Bromo-3-Fluoro-Pyridine-2-Carboxylic Acid Amide
CAS No.	1880080-54-5
Molecular Formula	C6H4BrFN2O
Molecular Weight	219.01 g/mol
Synonyms	2-Pyridinecarboxamide, 6-bromo-3-fluoro-; 6-Bromo-3-fluoropicolinamide; 3-Fluoro-6-bromopyridine-2-carboxamide; 6-Bromo-3-fluoropyridine-2-carboxylic acid amide; 2-Carbamoyl-6-bromo-3-fluoropyridine; 6-Bromo-3-fluoro-2-pyridinecarboxamide; 1880080-54-5; 6-Br-3-F-Pyridine-2-CONH2
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Fluoro-Pyridine-2-Carboxylic Acid Amide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data, including HPLC purity, NMR, and MS confirmation, upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light as indicated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.