Description

1-{(1S,2R)-1-[(11Br)-2,6-Dimethyldinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yloxy]-1-Phenylpropan-2-Yl}-3-Phenylurea is a sophisticated chiral organophosphorus compound designed for advanced synthetic applications. Its value lies in its role as a highly selective ligand or catalyst precursor in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. This product is essential for R&D scientists and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metal-catalyzed reactions, including hydrogenation, cross-coupling, and C-H activation.
• Pharmaceutical Intermediate Synthesis: Key building block in the research and development of novel active pharmaceutical ingredients (APIs) with specific stereocenters.
• Agrochemical Research: Used in the synthesis of chiral pesticides and herbicides where biological activity is stereospecific.
• Methodology Development: A valuable tool for academic and industrial researchers developing new asymmetric synthetic protocols.
• Fine Chemical Production: Enables the commercial-scale manufacture of enantiomerically enriched flavors, fragrances, and advanced materials.

Basic Information

Product Name	1-{(1S,2R)-1-[(11Br)-2,6-Dimethyldinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yloxy]-1-Phenylpropan-2-Yl}-3-Phenylurea
CAS No.	1858223-86-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(11Br)-2,6-Dimethyldinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl (1S,2R)-1-(3-phenylureido)-1-phenylpropan-2-yl ether; Chiral Dinaphthodioxaphosphepin Urea Derivative; Asymmetric Phosphite-Urea Hybrid Ligand; CAS 1858223-86-5
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) are available upon request, detailing specifications such as chiral purity by HPLC and residual solvent content.

Storage

Preserve in a tightly closed container under an inert atmosphere (e.g., nitrogen or argon), protected from light, and in a cool, dry place. Due to its hygroscopic and easily oxidized nature, the container should be opened only under controlled, moisture-free conditions. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.